Livedo Reticularis With Perineural and Intraneural Mucin Deposition in a Child With AT-III Deficiency: A Case Suggestive of Neuropathia Mucinosa Cutanea?

This case expands the spectrum of intraneural mucin deposition by associating it with severe AT-III deficiency. Although fulfilling the morphologic description of NMC, the findings could also reflect a reactive change to ischemic nerve injury rather than a primary mucinous neuropathy. Further reports integrating clinical and histopathologic data are needed to clarify whether NMC represents a unique neurocutaneous disorder or a nonspecific reactive phenomenon.