Development of a Compact FFL-MPI System Based on a Halbach Permanent Magnet

The high power consumption and large size of conventional Magnetic Particle Imaging (MPI) systems present significant barriers to their clinical translation. To address this challenge, we present a novel, compact MPI scanner implementation based on a Halbach permanent magnet structure. This design generates a field-free line (FFL) and achieves a gradient strength of 1.16 T/m within a 50 mm diameter bore. Experimental results demonstrate that the system successfully resolves two distinct particle points separated by 1 mm, confirming a spatial resolution better than 1 mm. Our findings position this low-power, Halbach-based MPI scanner as a promising tool for molecular imaging laboratories and a significant step towards future human-scale applications.

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Publication Details

Journal
Infinite Science GmbH
Published
2025-11-03
DOI
https://doi.org/10.18416/ijmpi.2026.2603046
Primary Topic
Characterization and Applications of Magnetic Nanoparticles
Type
article
Field-Weighted Citation Impact
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article

Development of a Compact FFL-MPI System Based on a Halbach Permanent Magnet

Y. H. Zheng, Wuhu Feng, Feiyang Liao, Lilei Dong et al.
Infinite Science GmbH
Characterization and Applications of Magnetic Nanoparticles
article

Development of a Compact FFL-MPI System Based on a Halbach Permanent Magnet

Y. H. Zheng, Wuhu Feng, Feiyang Liao, Lilei Dong, Yajie Xu, Zhongyi Wu, Yilin Yang, Zhiyuan Hou, Haipeng Lv, Jianlan Guo, Ya Wang
article en

Abstract

The high power consumption and large size of conventional Magnetic Particle Imaging (MPI) systems present significant barriers to their clinical translation. To address this challenge, we present a novel, compact MPI scanner implementation based on a Halbach permanent magnet structure. This design generates a field-free line (FFL) and achieves a gradient strength of 1.16 T/m within a 50 mm diameter bore. Experimental results demonstrate that the system successfully resolves two distinct particle points separated by 1 mm, confirming a spatial resolution better than 1 mm. Our findings position this low-power, Halbach-based MPI scanner as a promising tool for molecular imaging laboratories and a significant step towards future human-scale applications.

Infinite Science GmbH
Suzhou Institute of Biomedical Engineering and Technology (CN), JW Medical Systems (China) (CN)
Affordable and clean energy
Openalex Percentile: Top 36%
Characterization and Applications of Magnetic Nanoparticles
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