Resveratrol inhibits NLRP3 inflammasome activation to alleviate bovine mastitis by promoting PINK1-mediated mitophagy

This study demonstrates that resveratrol mitigates NLRP3-mediated inflammatory responses by activating PINK1-mediated mitophagy, suggesting its potential as a promising therapeutic candidate for mastitis in perinatal dairy cows experiencing negative energy balance.

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Publication Details

Journal
Animal Bioscience
Published
2026-03-11
DOI
https://doi.org/10.5713/ab.250935
Primary Topic
Milk Quality and Mastitis in Dairy Cows
Type
article
Field-Weighted Citation Impact
0.00
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article

Resveratrol inhibits NLRP3 inflammasome activation to alleviate bovine mastitis by promoting PINK1-mediated mitophagy

Chengmin Li, Longwei Sun, Weiguo Zhao, Ran Yu et al.
Animal Bioscience
Milk Quality and Mastitis in Dairy Cows
article

Resveratrol inhibits NLRP3 inflammasome activation to alleviate bovine mastitis by promoting PINK1-mediated mitophagy

Chengmin Li, Longwei Sun, Weiguo Zhao, Ran Yu, Shujing Tan, Junpen Huang
article en

Abstract

This study demonstrates that resveratrol mitigates NLRP3-mediated inflammatory responses by activating PINK1-mediated mitophagy, suggesting its potential as a promising therapeutic candidate for mastitis in perinatal dairy cows experiencing negative energy balance.

Animal Bioscience
Jiangsu University of Science and Technology (CN), Sericultural Research Institute (CN)
Openalex Percentile: Top 16%
Milk Quality and Mastitis in Dairy Cows
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