Cooking Up the Truth: Heat-Damaged RBC Imaging in a Case of Suspected Lymphoma

We present the case of a patient with an elevated prostate-specific antigen level who underwent a prostate MRI that revealed a mass between the prostate and rectum, prompting further evaluation. Biopsy suggested low-grade B-cell lymphoma. A staging ¹⁸F-FDG PET/CT demonstrated a mildly avid pelvic mass and abdominal splenosis. Heat-damaged red blood cell scintigraphy showed uptake consistent with splenosis in the pelvis. A review of outside pathology confirmed no evidence of lymphoma, establishing splenosis as the diagnosis.