Observation on the Efficacy of Nano-Silver Dressing Combined With Silver Sulfadiazine Cream in the Treatment of Second-Degree Burn Wounds

This study explored the therapeutic effect of nanosilver dressing combined with silver sulfadiazine cream on burn wounds. A total of 100 patients treated between January 2022 and March 2023 were randomly divided into 2 groups: a control group (silver sulfadiazine cream alone, n=50) and an observation group (nanosilver dressing plus silver sulfadiazine, n=50). Clinical efficacy, complication rate, wound healing time, bacterial infection rate, pigmentation fading time, and inflammatory factor levels were compared. The total effective rate of the observation group (97%) was significantly higher than that of the control group (88%). The incidence of complications in the observation group (10%) was significantly lower than that in the control group (64%). On the 7th, 12th, and 17th day of treatment, the wound healing rate of the observation group was higher than that of the control group, and the wound healing time was shorter than that of the control group. The pigmentation subsidence time of the observation group was significantly shorter than that of the control group. After treatment, the levels of inflammatory factors TNF-α and IL-6 and CRP indicators in the observation group were significantly lower than those in the control group. The bacterial infection rate in the nanosilver antibacterial dressing group was significantly lower than that in the silver sulfadiazine cream group. Nano-silver dressing combined with silver sulfadiazine cream has a significant therapeutic effect on burn wounds, which can improve the overall treatment efficiency, shorten wound healing time, pigmentation subsidence time, and reduce inflammatory reaction.

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Journal
Journal of Craniofacial Surgery
Published
2026-03-16
DOI
https://doi.org/10.1097/scs.0000000000012339
Primary Topic
Wound Healing and Treatments
Type
article
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article

Observation on the Efficacy of Nano-Silver Dressing Combined With Silver Sulfadiazine Cream in the Treatment of Second-Degree Burn Wounds

Yacui Yuan, H. S. Li, Yang Zhang, Wan Jiang et al.
Journal of Craniofacial Surgery
Wound Healing and Treatments
article

Observation on the Efficacy of Nano-Silver Dressing Combined With Silver Sulfadiazine Cream in the Treatment of Second-Degree Burn Wounds

Yacui Yuan, H. S. Li, Yang Zhang, Wan Jiang, Congying Zhao, Huanmin Qu, Baoping Du, Wei Jiang, Na Zhang, Qianfeng He
article en

Abstract

This study explored the therapeutic effect of nanosilver dressing combined with silver sulfadiazine cream on burn wounds. A total of 100 patients treated between January 2022 and March 2023 were randomly divided into 2 groups: a control group (silver sulfadiazine cream alone, n=50) and an observation group (nanosilver dressing plus silver sulfadiazine, n=50). Clinical efficacy, complication rate, wound healing time, bacterial infection rate, pigmentation fading time, and inflammatory factor levels were compared. The total effective rate of the observation group (97%) was significantly higher than that of the control group (88%). The incidence of complications in the observation group (10%) was significantly lower than that in the control group (64%). On the 7th, 12th, and 17th day of treatment, the wound healing rate of the observation group was higher than that of the control group, and the wound healing time was shorter than that of the control group. The pigmentation subsidence time of the observation group was significantly shorter than that of the control group. After treatment, the levels of inflammatory factors TNF-α and IL-6 and CRP indicators in the observation group were significantly lower than those in the control group. The bacterial infection rate in the nanosilver antibacterial dressing group was significantly lower than that in the silver sulfadiazine cream group. Nano-silver dressing combined with silver sulfadiazine cream has a significant therapeutic effect on burn wounds, which can improve the overall treatment efficiency, shorten wound healing time, pigmentation subsidence time, and reduce inflammatory reaction.

Journal of Craniofacial Surgery
Xian Central Hospital (CN), Military University (RU), Shaanxi University of Science and Technology (CN)
Good health and well-being
Openalex Percentile: Top 18%
Wound Healing and Treatments
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