Febrile transfusion‐associated circulatory overload in adult oncology patients

We found an association of TACO and new fever in 16% of cases compared with 32% reported in a non-exclusive oncological setting. Findings are likely related to impaired immune response present in cancer patients associated with immunosuppression. Our findings support that fever should not be used to distinguish transfusion-related acute lung injury (TRALI) from TACO.

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Publication Details

Journal
Vox Sanguinis
Published
2026-03-17
DOI
https://doi.org/10.1111/vox.70237
Primary Topic
Blood transfusion and management
Type
article
Field-Weighted Citation Impact
0.00
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article

Febrile transfusion‐associated circulatory overload in adult oncology patients

Roland L. Bassett, Adriana Maria Knopfelmacher, Colleen Villamin, Marisol Maldonado et al.
Vox Sanguinis
Blood transfusion and management
article

Febrile transfusion‐associated circulatory overload in adult oncology patients

Roland L. Bassett, Adriana Maria Knopfelmacher, Colleen Villamin, Marisol Maldonado, Roman Gonta, Kimberly Klein, Mayrin Correa Medina, James Kelley, Fernando Martinez
article en

Abstract

We found an association of TACO and new fever in 16% of cases compared with 32% reported in a non-exclusive oncological setting. Findings are likely related to impaired immune response present in cancer patients associated with immunosuppression. Our findings support that fever should not be used to distinguish transfusion-related acute lung injury (TRALI) from TACO.

Vox Sanguinis
The University of Texas MD Anderson Cancer Center (US), University of Miami (US), Moffitt Cancer Center (US), Matrix Institute on Addictions (US)
Good health and well-being
Openalex Percentile: Top 20%
Blood transfusion and management
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