187eP Prognostic nutritional index predicting outcomes in advanced non-small cell lung cancer: A multivariate analysis from University Hospitals of Leicester (UHL) retrospective cohort
The prognostic nutritional index (PNI), derived from serum albumin and lymphocyte count, reflects systemic nutritional and immune status and has been associated with cancer outcomes. We evaluated the association between pretreatment PNI and clinical outcomes in patients with advanced non-small cell lung cancer (NSCLC) receiving first-line immune checkpoint inhibitors (ICIs), with or without chemotherapy, accounting for age, ECOG performance status (PS), PD-L1 status, body mass index, and comorbidities.
Authors
- Hsu Phern Chong (ORCID: https://orcid.org/0000-0002-4662-3882)
- David Adebayo
- H.A. Chauhan
- S. Sharma
- M. Chauhan
- A. Sultan
- S. Dulloo
- S. Ahmed
Institutions
- University of Leicester (GB)
- Leicester Royal Infirmary (GB)
- University Hospitals of Leicester NHS Trust (GB)
Publication Details
- Journal
- ESMO Open
- Published
- 2026-03-17
- DOI
- https://doi.org/10.1016/j.esmoop.2026.106494
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00