Implications of inflammasomes in dental pulp inflammation: immunopathology and therapeutic targeting
Although preclinical studies were promising, comprehensive clinical trials of IL-1 family and inflammasome inhibitors are required for translating current research into viable treatments for patients with dental pulpitis. Future work should prioritize clinical validation to enable implementation in patient care.
Authors
- Mohammad Javad Yousefi (ORCID: https://orcid.org/0000-0003-1886-3851)
- Kiarash Saleki (ORCID: https://orcid.org/0000-0003-4159-7299)
- Yashmin Afshar
- Nima Rezaei
Institutions
- Education and Research Network (IN)
- Universal Scientific Education and Research Network (IR)
- Tehran University of Medical Sciences (IR)
- Babol University of Medical Sciences (IR)
Publication Details
- Journal
- Immunopharmacology and Immunotoxicology
- Published
- 2026-03-17
- DOI
- https://doi.org/10.1080/08923973.2026.2625040
- Primary Topic
- Endodontics and Root Canal Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00