BKDRP: a biological knowledge-driven approach for drug response prediction using multi-omics data in cancer cell lines
In conclusion, BKDRP presents a novel biological knowledge-driven deep neural network model for cancer drug response prediction that shows strong predictive accuracy and interpretability. By integrating multi-omics data and incorporating domain knowledge, BKDRP has the strong potential for applications in biomarker discovery and the advancement of personalized oncology.
Authors
- Koyel Mandal (ORCID: https://orcid.org/0000-0003-0453-7828)
- Sanghamitra Bandyopadhyay
Institutions
- Indian Statistical Institute (IN)
Publication Details
- Journal
- BMC Bioinformatics
- Published
- 2026-03-17
- DOI
- https://doi.org/10.1186/s12859-026-06406-2
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00