Distinct Association of MRE11 and ATM Co-Expression With Clinical Outcomes in Laryngeal Cancer
High immunohistochemical expression of MRE11 and ATM proteins was associated with earlier clinical stages and better treatment outcomes in laryngeal carcinoma, particularly when both proteins were elevated. The results point to the potential of MRE11 and ATM as predictors of treatment response, but more extensive molecular and clinical research would be needed to gain a more detailed insight.
Authors
- Miloslav Pála (ORCID: https://orcid.org/0000-0002-8446-6339)
- Radka Lohynská (ORCID: https://orcid.org/0000-0003-1379-9264)
- Tereza Drbohlavová
- Marián Švajdler (ORCID: https://orcid.org/0000-0001-8052-4741)
- Petra Tesařová (ORCID: https://orcid.org/0000-0003-3607-3474)
- Zdeňka Pechačová (ORCID: https://orcid.org/0000-0002-6292-9814)
- Zuzana Spurkova
- Vratislav Sedivec
Publication Details
- Journal
- Oncology
- Published
- 2026-03-17
- DOI
- https://doi.org/10.1159/000551450
- Primary Topic
- DNA Repair Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00