Predicting oral cephalosporin susceptibility in <i>Escherichia coli</i> blood isolates using parenteral cephalosporin susceptibility testing

Prediction of oral second-generation cephalosporins may warrant cefazolin MIC ≤2 mg/L, despite limitations regarding false resistance and susceptibility discordant. Ceftriaxone/cefotaxime demonstrates a more reliable surrogate for predicting oral third-generation cephalosporins susceptibility. Future investigations are necessary to clinically corroborate these findings.

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Publication Details

Journal
Journal of Antimicrobial Chemotherapy
Published
2026-03-04
DOI
https://doi.org/10.1093/jac/dkag093
Primary Topic
Bacterial Identification and Susceptibility Testing
Type
article
Field-Weighted Citation Impact
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article

Predicting oral cephalosporin susceptibility in Escherichia coli blood isolates using parenteral cephalosporin susceptibility testing

Vanthida Huang, Tho H Pham, Kyle C. Molina
Journal of Antimicrobial Chemotherapy
Bacterial Identification and Susceptibility Testing
article

Predicting oral cephalosporin susceptibility in Escherichia coli blood isolates using parenteral cephalosporin susceptibility testing

Vanthida Huang, Tho H Pham, Kyle C. Molina
article en

Abstract

Prediction of oral second-generation cephalosporins may warrant cefazolin MIC ≤2 mg/L, despite limitations regarding false resistance and susceptibility discordant. Ceftriaxone/cefotaxime demonstrates a more reliable surrogate for predicting oral third-generation cephalosporins susceptibility. Future investigations are necessary to clinically corroborate these findings.

Journal of Antimicrobial ChemotherapyVol. 81(4)
Midwestern University (US), Scripps Health (US), University of Arizona (US), Scripps Mercy Hospital (US), Phoenix College (US), University of Colorado Denver (US)
Good health and well-being
Openalex Percentile: Top 16%
Bacterial Identification and Susceptibility Testing
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