Assessing Major Adverse Liver Outcomes With Baclofen Compared to Acamprosate in Compensated Alcohol‐Associated Cirrhosis

In this large real-world study, baclofen was associated with a higher risk of hepatic encephalopathy compared with acamprosate in patients with compensated alcohol-associated cirrhosis.

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Publication Details

Journal
Alimentary Pharmacology & Therapeutics
Published
2026-03-17
DOI
https://doi.org/10.1111/apt.70619
Primary Topic
Alcohol Consumption and Health Effects
Type
article
Field-Weighted Citation Impact
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article

Assessing Major Adverse Liver Outcomes With Baclofen Compared to Acamprosate in Compensated Alcohol‐Associated Cirrhosis

Walid S. Ayoub, Hirsh D. Trivedi, Aarshi Vipani, Ellen Choi et al.
Alimentary Pharmacology & Therapeutics
Alcohol Consumption and Health Effects
article

Assessing Major Adverse Liver Outcomes With Baclofen Compared to Acamprosate in Compensated Alcohol‐Associated Cirrhosis

Walid S. Ayoub, Hirsh D. Trivedi, Aarshi Vipani, Ellen Choi, Y. Wang, Parnian Naji, Sepideh Mehravar, Hyun‐seok Kim, Yee Hui Yeo, Julie Yang, Chun‐Ying Wu, Alexander Kuo, Lorenzo Leggio, Juan Pablo Arab
article en

Abstract

In this large real-world study, baclofen was associated with a higher risk of hepatic encephalopathy compared with acamprosate in patients with compensated alcohol-associated cirrhosis.

Alimentary Pharmacology & Therapeutics
Cedars-Sinai Medical Center (US), National Institute on Drug Abuse (US), National Yang Ming Chiao Tung University (TW), Virginia Commonwealth University (US), University Hospitals of Cleveland (US), Englewood Hospital and Medical Center (US), National Institute on Alcohol Abuse and Alcoholism (US), The University of Texas at Austin (US)
Good health and well-being
Openalex Percentile: Top 20%
Alcohol Consumption and Health Effects
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