Association of body mass index, waist circumference, (abdominal) overweight and obesity with sex- and age-specific cognitive function over time—the Doetinchem Cohort Study

In both sexes, higher BMI and WC were consistently associated with worse cognition. WC-based overweight and obesity showed larger effect sizes with cognition than BMI-based overweight and obesity. Only in men, associations with cognitive decline and effect modification by age were observed.

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Publication Details

Journal
International Journal of Obesity
Published
2026-03-17
DOI
https://doi.org/10.1038/s41366-026-02034-1
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
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article

Association of body mass index, waist circumference, (abdominal) overweight and obesity with sex- and age-specific cognitive function over time—the Doetinchem Cohort Study

Kirsten E. J. Wesenhagen, Femke te Hoonte, H. Susan J. Picavet, M. Liset Rietman et al.
International Journal of Obesity
Dementia and Cognitive Impairment Research
article

Association of body mass index, waist circumference, (abdominal) overweight and obesity with sex- and age-specific cognitive function over time—the Doetinchem Cohort Study

Kirsten E. J. Wesenhagen, Femke te Hoonte, H. Susan J. Picavet, M. Liset Rietman, W. M. Monique Verschuren
article en

Abstract

In both sexes, higher BMI and WC were consistently associated with worse cognition. WC-based overweight and obesity showed larger effect sizes with cognition than BMI-based overweight and obesity. Only in men, associations with cognitive decline and effect modification by age were observed.

International Journal of Obesity
Utrecht University (NL), University Medical Center Utrecht (NL), National Institute for Public Health and the Environment (NL)
Zero hunger
Openalex Percentile: Top 28%
Dementia and Cognitive Impairment Research
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