Network pharmacology and bioinformatics analysis of the multi-target immune-inflammatory mechanisms of Shengma Gegen decoction in chronic urticaria
SMGG may ameliorate CU by coordinately regulating inflammatory pathways (AGE-RAGE, TNF, IL-17) and immune balance via core targets (MMP9, IL6, AKT1, IL1B, TNF). The study offers a mechanistic basis and target/pathway prioritization to guide future experimental work and the modernization of traditional formulations.
Authors
- Jinhong Wu (ORCID: https://orcid.org/0000-0001-5754-1498)
- Yirong Ma (ORCID: https://orcid.org/0009-0005-8180-184X)
- Miao Hu (ORCID: https://orcid.org/0000-0001-5403-4095)
- Jiaming Li
Publication Details
- Journal
- International Journal of Clinical Pharmacology and Therapeutics
- Published
- 2026-03-17
- DOI
- https://doi.org/10.5414/cp204855
- Primary Topic
- Urticaria and Related Conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00