Biomarkers of endothelial glycocalyx dysfunction in pregnancy: a systematic review of clinical relevance and detection techniques
This review highlights the potential of glycocalyx-derived biomarkers and imaging tools as non-invasive indicators of microvascular injury. Their integration into existing surveillance models could enhance early risk stratification and open new avenues for targeted clinical interventions in cardio-obstetric care.
Authors
- Francesco De Seta (ORCID: https://orcid.org/0000-0003-1611-0813)
- Valentina Di Micoli (ORCID: https://orcid.org/0000-0001-9064-0826)
- Katariina Öörni (ORCID: https://orcid.org/0000-0002-9525-0250)
- Federica Fogacci (ORCID: https://orcid.org/0000-0001-7853-0042)
- Cristina Scollo
- Duha Yahya
- Arrigo Francesco Giuseppe Cicero
- Claudio Borghi
- Jeanine Roeters Van Lennep
Institutions
- University of Helsinki (FI)
- Vita-Salute San Raffaele University (IT)
- Erasmus MC (NL)
- Istanbul Medipol University (TR)
- Wihuri Research Institute (FI)
- Azienda USL di Bologna (IT)
- Atatürk University (TR)
- University of Bologna (IT)
Publication Details
- Journal
- Inflammation Research
- Published
- 2026-03-17
- DOI
- https://doi.org/10.1007/s00011-026-02208-7
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00