Using reciprocally retained gene families to detect whole-genome multiplications in plants
Although none of the reciprocally retained gene families is a perfect WGM marker on its own, we show that using an extended set of such families as input for birth-death and <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msub><mml:mi>K</mml:mi><mml:mtext>S</mml:mtext></mml:msub></mml:math> distribution modeling approaches leads to better WGM detection performance than using entire genomes. A pipeline to use reciprocally retained gene families for <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msub><mml:mi>K</mml:mi><mml:mtext>S</mml:mtext></mml:msub></mml:math> distribution-based WGM inference in angiosperms has been implemented in ksrates v2.0.
Authors
- Cecilia Sensalari (ORCID: https://orcid.org/0000-0003-4390-6534)
- Steven Maere (ORCID: https://orcid.org/0000-0002-5341-136X)
- Setareh Tasdighian (ORCID: https://orcid.org/0000-0002-7411-0136)
Institutions
- Ghent University (BE)
- VIB-UGent Center for Plant Systems Biology (BE)
- VIB-UGent Center for Inflammation Research (BE)
Publication Details
- Journal
- Genome biology
- Published
- 2026-03-17
- DOI
- https://doi.org/10.1186/s13059-026-04032-y
- Primary Topic
- Genomic variations and chromosomal abnormalities
- Type
- article
- Field-Weighted Citation Impact
- 0.00