Prevalence and risk factors of gross neurologic deficits in children after severe malaria: A systematic review and meta-analysis
Gross neurologic deficits are more prevalent in children in Sub-Saharan Africa with CM compared to severe malaria in general, and a number of clinical factors in children with CM increase the risk. Interventions by clinicians should target children with CM at highest risk during admission.
Authors
- Kevin Ouma Ojiambo
- Caroline Otike
- Ekwaro A. Obuku (ORCID: https://orcid.org/0000-0001-5311-2346)
- Andrea L. Conroy (ORCID: https://orcid.org/0000-0002-5328-6511)
- Allen Eva Okullo (ORCID: https://orcid.org/0000-0001-7841-8413)
- Simple Ouma (ORCID: https://orcid.org/0000-0002-4510-6736)
- Alison Annet Kinengyere (ORCID: https://orcid.org/0000-0002-5341-3218)
- Michael Boele van Hensbroek
- Moses Ocan
- Chandy C. John
- Richard Idro
Institutions
- Indiana University Health (US)
- London School of Hygiene & Tropical Medicine (GB)
- World Health Organization - Uganda (UG)
- Amsterdam University Medical Centers (NL)
- Joint Clinical Research Centre (UG)
- Indiana University – Purdue University Indianapolis (US)
- Makerere University (UG)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-03-17
- DOI
- https://doi.org/10.1371/journal.pone.0333258
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00