Gestational diabetes in South African women with HIV and HIV-seronegative women: Results from the ORCHID cohort

GDM prevalence in South Africa is similar to North America/Europe. Early GDM was diagnosed in a large majority of women who also exhibited features of poorer insulin sensitivity and beta cell function than those diagnosed late in pregnancy or without GDM. WWH had lower GDM risk than HIV-seronegative women. Future studies to understand the implications of early GDM in African populations are warranted.

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Publication Details

Journal
The Journal of Clinical Endocrinology & Metabolism
Published
2026-03-15
DOI
https://doi.org/10.1210/clinem/dgag111
Primary Topic
Gestational Diabetes Research and Management
Type
article
Field-Weighted Citation Impact
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article

Gestational diabetes in South African women with HIV and HIV-seronegative women: Results from the ORCHID cohort

Allison Zerbe, Elton Mukonda, Jody Rusch, Jami L. Josefson et al.
The Journal of Clinical Endocrinology & Metabolism
Gestational Diabetes Research and Management
article

Gestational diabetes in South African women with HIV and HIV-seronegative women: Results from the ORCHID cohort

Allison Zerbe, Elton Mukonda, Jody Rusch, Jami L. Josefson, Elaine J. Abrams, Julia H. Goedecke, Hlengiwe P. Madlala, Justine Legbedze, Sandisiwe Matyesini, L Myer, Grace McComsey, Jennifer Jao, Patrick Catalano
article en

Abstract

GDM prevalence in South Africa is similar to North America/Europe. Early GDM was diagnosed in a large majority of women who also exhibited features of poorer insulin sensitivity and beta cell function than those diagnosed late in pregnancy or without GDM. WWH had lower GDM risk than HIV-seronegative women. Future studies to understand the implications of early GDM in African populations are warranted.

The Journal of Clinical Endocrinology & Metabolism
National Health Laboratory Service (ZA), South African Medical Research Council (ZA), Northwestern University (US), Lurie Children's Hospital (US), Cleveland Clinic (US), University of Cape Town (ZA), Groote Schuur Hospital (ZA), Massachusetts General Hospital (US), Case Western Reserve University (US), Columbia University (US)
Good health and well-being
Openalex Percentile: Top 18%
Gestational Diabetes Research and Management
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Gestational diabetes in South African women with HIV and HIV-seronegative women: Results from the ORCHID cohort — Allison Zerbe, Elton Mukonda, et al. · The Journal of Clinical Endocrinology & Metabolism (2026) | TGRS Research Map | TGRS