Effectiveness analysis and clinical application potential exploration of combined detection of PAX1/JAM3 gene methylation in early diagnosis of cervical precancerous lesions

PAX1/JAM3 gene methylation testing demonstrates strong diagnostic efficacy for cervical precancerous lesions and holds significant potential in triage diagnosis. The PAX1/SOX1 panel also shows promise as a complementary biomarker.

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Publication Details

Journal
Clinical Epigenetics
Published
2026-03-17
DOI
https://doi.org/10.1186/s13148-026-02095-z
Primary Topic
Cervical Cancer and HPV Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Effectiveness analysis and clinical application potential exploration of combined detection of PAX1/JAM3 gene methylation in early diagnosis of cervical precancerous lesions

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Clinical Epigenetics
Cervical Cancer and HPV Research
article

Effectiveness analysis and clinical application potential exploration of combined detection of PAX1/JAM3 gene methylation in early diagnosis of cervical precancerous lesions

Ma Xiumin, Yu Xiaolu, Yiliminuer Keremu, Kong Weina, Xu Xiaohui, Guo Fan
article en

Abstract

PAX1/JAM3 gene methylation testing demonstrates strong diagnostic efficacy for cervical precancerous lesions and holds significant potential in triage diagnosis. The PAX1/SOX1 panel also shows promise as a complementary biomarker.

Clinical Epigenetics
Xinjiang Medical University (CN), Tumor Hospital of Xinjiang Medical University (CN)
Good health and well-being
Openalex Percentile: Top 21%
Cervical Cancer and HPV Research
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