Mental and Behavioral Disorders Associated with the Use of Psychoactive Substances: Opioids, Cannabinoids, and Other Drugs

Mental and behavioral disorders related to psychoactive substance use represent a significant public health problem worldwide. Psychoactive substances such as opioids, cannabinoids, stimulants, and sedatives influence the central nervous system, leading to alterations in mood, cognition, perception, and behavior. Persistent use can result in substance dependence, withdrawal syndromes, and psychiatric comorbidities. This research article explores the epidemiology, clinical manifestations, and management of mental and behavioral disorders associated with psychoactive substances, focusing particularly on opioids and cannabinoids. Using secondary analysis of published literature and global health data, the study highlights the mechanisms underlying substance use disorders and the impact on individual and societal health. Findings suggest that substance use disorders are multifactorial conditions influenced by biological, psychological, and social factors. Effective management requires an integrated approach including pharmacological treatment, psychosocial interventions, and preventive strategies. The study emphasizes the importance of early identification and comprehensive treatment to reduce the burden of substance-related mental health disorders.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-03-12
DOI
https://doi.org/10.5281/zenodo.18984416
Primary Topic
Opioid Use Disorder Treatment
Type
article
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article

Mental and Behavioral Disorders Associated with the Use of Psychoactive Substances: Opioids, Cannabinoids, and Other Drugs

S. Nurdinova, Prakash Kumar, Navaneethselvan Murgapandi
Zenodo (CERN European Organization for Nuclear Research)
Opioid Use Disorder Treatment
article

Mental and Behavioral Disorders Associated with the Use of Psychoactive Substances: Opioids, Cannabinoids, and Other Drugs

S. Nurdinova, Prakash Kumar, Navaneethselvan Murgapandi
article en

Abstract

Mental and behavioral disorders related to psychoactive substance use represent a significant public health problem worldwide. Psychoactive substances such as opioids, cannabinoids, stimulants, and sedatives influence the central nervous system, leading to alterations in mood, cognition, perception, and behavior. Persistent use can result in substance dependence, withdrawal syndromes, and psychiatric comorbidities. This research article explores the epidemiology, clinical manifestations, and management of mental and behavioral disorders associated with psychoactive substances, focusing particularly on opioids and cannabinoids. Using secondary analysis of published literature and global health data, the study highlights the mechanisms underlying substance use disorders and the impact on individual and societal health. Findings suggest that substance use disorders are multifactorial conditions influenced by biological, psychological, and social factors. Effective management requires an integrated approach including pharmacological treatment, psychosocial interventions, and preventive strategies. The study emphasizes the importance of early identification and comprehensive treatment to reduce the burden of substance-related mental health disorders.

Zenodo (CERN European Organization for Nuclear Research)
Osh State University (KG)
Good health and well-being
Openalex Percentile: Top 23%
Opioid Use Disorder Treatment
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