Decellularized ovarian bioscaffolds and resveratrol-loaded polymeric nanoparticles support in vitro viability and ultrastructural preservation of bovine preantral follicles
The decellularization protocol effectively removed cellular content and preserved ECM structure and ultrastructure. 3D culture system combined with supplementation of 0.02 µM RLNP supported follicular viability and ultrastructural preservation and was associated with transcriptional changes in antioxidant-related genes.
Authors
- Ernando Igo Teixeira de Assis
- Francisco C. Costa (ORCID: https://orcid.org/0000-0002-7045-1523)
- Danisvânia Ripardo Nascimento (ORCID: https://orcid.org/0000-0001-6572-6257)
- Miguel Fernandes de Lima Neto
- Mariana Aragão Matos Donato (ORCID: https://orcid.org/0000-0002-3361-2789)
- Venância Antônia Nunes Azevedo (ORCID: https://orcid.org/0000-0003-3194-8913)
- Alice Vitória Frota Reis
- A.A. Silva
- Regislane Pinto Ribeiro (ORCID: https://orcid.org/0009-0008-2607-7598)
- Bianca Régia Silva
- José Roberto Viana Silva
- Josimar Oliveira Eloy
Institutions
- Universidade Estadual do Ceará (BR)
- Universidade Federal do Ceará (BR)
- Universidade Federal de Pernambuco (BR)
Publication Details
- Journal
- Journal of Assisted Reproduction and Genetics
- Published
- 2026-03-17
- DOI
- https://doi.org/10.1007/s10815-026-03823-3
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 0.00