Biphasic Change in Retinal Arterial Hemodynamics Amidst Systematic Perfusion Decline With Increasing Degree of Myopia

This study conducted a detailed assessment of the hemodynamics of retinal vessels at different levels of myopia with AOSLO, revealing severity-dependent alterations characterized by elevated vascular resistance, reduced retinal perfusion, and biphasic arterial response. These hemodynamic alterations were closely correlated with fundus structural changes, suggesting vascular dysregulation may be a contributing factor to the pathophysiological changes associated with increasing severity of myopia.