Postoperative Inflammation and Pain Management with Intracanalicular Dexamethasone Insert: Real-World Applications
We present a comprehensive review of the current therapeutic landscape for management of postoperative pain and inflammation following cataract surgery, including the limitations of topical eye drop medications. We review data from the key phase 2 and 3 clinical trials that supported the approval and label expansion for DEX. We also summarize the broader literature of smaller studies evaluating the role of DEX in controlling postoperative pain and inflammation for a variety of ophthalmic surgery beyond cataract surgery as well as in management of ocular itching associated with allergic conjunctivitis.
Authors
- Aditi Bauskar (ORCID: https://orcid.org/0000-0001-7595-6267)
- Trung Hiếu Trần
- Kendall E. Donaldson (ORCID: https://orcid.org/0000-0002-1361-6264)
- Srilatha Vantipalli (ORCID: https://orcid.org/0000-0002-4108-5149)
- Michael H. Goldstein (ORCID: https://orcid.org/0000-0001-6672-3752)
- Eric D. Donnenfeld (ORCID: https://orcid.org/0000-0002-5235-1780)
- Savak Teymoorian
- Jordan Graff
- Cathleen McCabe
Institutions
- Creighton University (US)
- Citrix (Switzerland) (CH)
- University of Arizona (US)
- University of Miami (US)
- University of Phoenix (US)
- Vision Eye Institute (AU)
- United States Virgin Islands Department of Health (VI)
- Eye Care Associates (US)
- Harvard Eye Associates (US)
Publication Details
- Journal
- Ophthalmology and Therapy
- Published
- 2026-03-17
- DOI
- https://doi.org/10.1007/s40123-026-01357-6
- Primary Topic
- Anesthesia and Pain Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00