Predictive factors of successful renal replacement therapy weaning

The UNDERSCORE, derived from a homogeneous conservative RRT initiation cohort and validated in a diverse ICU population, provides a bedside tool to estimate the probability of sustained RRT discontinuation after an initial clinician-initiated stop.

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Publication Details

Journal
Intensive Care Medicine
Published
2026-03-17
DOI
https://doi.org/10.1007/s00134-026-08357-x
Primary Topic
Acute Kidney Injury Research
Type
article
Field-Weighted Citation Impact
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article

Predictive factors of successful renal replacement therapy weaning

Sébastien Besset, Florent Poirson, Béatrice La Combe, Karim Lakhal et al.
Intensive Care Medicine
Acute Kidney Injury Research
article

Predictive factors of successful renal replacement therapy weaning

Sébastien Besset, Florent Poirson, Béatrice La Combe, Karim Lakhal, Alexandre Boyer, Saïd Lebbah, Guillaume Lacave, Didier Thévenin, Julien Maizel, Elisabeth Coupez, Philippe Markowicz, Florence Tubach, Laurent Martin Lefèvre, Bruno Mégarbane, Frédérique Schortgen, Guillaume Géri, Cyril Cadoz, Guillaume Chevrel, David Legouis, Marion Beuzelin, Sébastien Moschietto, Alain Combes, Marina Thirion, Adrien Robine, David Hajage, Bertrand Pons, Julio Badie, Laurent Martin Lefevre, Nicolas Lerolle, Alexandre Lautrette, Saad Nseir, Pascal Andreu, Karim Asehnoune, Guillaume Thiery, Frederic Sangla, Dimitri Titeca-Beauport, Eric Boulet, Bertrand Rozec, Jean-Pierre Quenot, Didier Dreyfuss, Saber Barbar, Marc Leone, Khalil Chaïbi, Jean-Damien Ricard, Nicolas Chudeau, Anne Bretagnol, Nicolas de Prost, Laurent Argaud, Christophe Vinsonneau, Hodane Yonis, Julien Mayaux, Nadia Aissaoui, Steven Grange, on behalf of the STOPDAPT-3 Investigators, Jean-Marie Forel, Julien Bohe, Guillaume Louis, Dorothée Carpentier, Stéphane Gaudry, Yanis Akrour, Kada Klouche, Jean Reignier
article en

Abstract

The UNDERSCORE, derived from a homogeneous conservative RRT initiation cohort and validated in a diverse ICU population, provides a bedside tool to estimate the probability of sustained RRT discontinuation after an initial clinician-initiated stop.

Intensive Care Medicine
University of Geneva (CH), Harvard University (US), Inserm (FR), Délégation Paris 7 (FR), Université de Bourgogne (FR), Université Paris Cité (FR), Sorbonne Université (FR), Hôpital Louis-Mourier (FR), Université Sorbonne Paris Nord (FR), Assistance Publique – Hôpitaux de Paris (FR), University Hospital of Geneva (CH), Centre Hospitalier Régional de Metz-Thionville (FR), Laboratoire Informatique d'Avignon (FR), Hôpital Avicenne (FR), Institut Pierre Louis d‘Épidémiologie et de Santé Publique (FR), Centre de recherche Translationnelle en Médecine moléculaire (FR), Centre Hospitalier Universitaire Pointe-à-Pitre (GP), Centre Hospitalier Départemental Vendée (FR), Centre Hospitalier René-Dubos (FR), French Clinical Research Infrastructure Network (FR), Maladies rénales fréquentes et rares : des mécanismes moléculaires à la médecine personnalisée, Geneva College (US)
Zero hunger
Openalex Percentile: Top 29%
Acute Kidney Injury Research
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