256P Impact of surgical extent on recurrence-free survival in STAS-positive non-small cell lung cancer: A reconstructed IPD meta-analysis

SUVmax change as prognostic for PFS (HR low vs. high reduction 2.960, 95%CI 1.201-7.295,p=0.018), but not baseline tumor burden.Conclusions: Deep early morphological and metabolic response to induction immunochemotherapy and metastasis-directed SBRT was observed in synchronous oligometastatic NSCLC.Metabolic response of the primary tumor and not baseline tumor burden was associated with PFS.

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Journal
ESMO Open
Published
2026-03-17
DOI
https://doi.org/10.1016/j.esmoop.2026.106564
Primary Topic
Lung Cancer Research Studies
Type
article
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0.00
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article

256P Impact of surgical extent on recurrence-free survival in STAS-positive non-small cell lung cancer: A reconstructed IPD meta-analysis

Federico Cappuzzo, Virna Cerasoli, Edoardo Mercadante, Riccardo Tajè et al.
ESMO Open
Lung Cancer Research Studies
article

256P Impact of surgical extent on recurrence-free survival in STAS-positive non-small cell lung cancer: A reconstructed IPD meta-analysis

Federico Cappuzzo, Virna Cerasoli, Edoardo Mercadante, Riccardo Tajè, Felicita Corzani, F.T. Gallina, Luigi Mosillo, Gabriele Alessandrini, F.L. Cecere, D. Forcella
article en

Abstract

SUVmax change as prognostic for PFS (HR low vs. high reduction 2.960, 95%CI 1.201-7.295,p=0.018), but not baseline tumor burden.Conclusions: Deep early morphological and metabolic response to induction immunochemotherapy and metastasis-directed SBRT was observed in synchronous oligometastatic NSCLC.Metabolic response of the primary tumor and not baseline tumor burden was associated with PFS.

ESMO OpenVol. 11
Tumori Foundation (US), Istituti di Ricovero e Cura a Carattere Scientifico (IT), Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
Openalex Percentile: Top 18%
Lung Cancer Research Studies
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