The influence of TLR4 signaling on retinal ganglion cell survival and angiogenic response in a mouse model of oxygen-induced retinopathy
These findings underscore TLR4's pivotal role in the regulation of inflammatory responses and angiogenesis in ROP. Targeting TLR4 may represent a novel therapeutic approach to preserve retinal integrity and improve visual outcomes in at-risk populations, particularly in premature infants.
Authors
- Yasunari Munemasa
Institutions
- St. Marianna University School of Medicine (JP)
Publication Details
- Journal
- Biochemistry and Biophysics Reports
- Published
- 2026-03-17
- DOI
- https://doi.org/10.1016/j.bbrep.2026.102550
- Primary Topic
- Immune Response and Inflammation
- Type
- article
- Field-Weighted Citation Impact
- 0.00