Preoperative ctDNA Predicts Upstaging and Recurrence in High-Risk Non-Muscle Invasive Bladder Cancer Undergoing Radical Cystectomy
Detectable ctDNA status for high-risk NMIBC pre-RC was associated with worse RFS, increased risk of pathological upstaging, and locally advanced disease with lymph node metastasis.
Authors
- Reza Mehrazin (ORCID: https://orcid.org/0009-0007-8648-0410)
- Brendan L. Raizenne
- Sima P. Porten (ORCID: https://orcid.org/0000-0002-3948-4968)
- Anobel Y. Odisho (ORCID: https://orcid.org/0000-0003-0975-0812)
- Peter K. Wiklund
- Reuben BEN-DAVID
- John P. Sfakianos
- Carissa Chu
- Igor Duquesne
- Ahmed Eraky
Institutions
- University of California, San Francisco (US)
- UCSF Helen Diller Family Comprehensive Cancer Center (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- The Journal of Urology
- Published
- 2026-03-17
- DOI
- https://doi.org/10.1097/ju.0000000000005034
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00