107P Health-related quality of life with ivonescimab versus pembrolizumab for PD-L1 positive, non-small cell lung cancer (HARMONi-2): A randomised, double-blind, phase III study in China

In HARMONi-2 study, ivonescimab significantly improved progression free survival (PFS) compared with pembrolizumab in previously untreated patients with advanced PD-L1 positive non-small cell lung cancer (NSCLC), with manageable safety profile. Here we reported health-related quality of life (HRQoL) from HARMONi-2.

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Publication Details

Journal
ESMO Open
Published
2026-03-17
DOI
https://doi.org/10.1016/j.esmoop.2026.106414
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
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article

107P Health-related quality of life with ivonescimab versus pembrolizumab for PD-L1 positive, non-small cell lung cancer (HARMONi-2): A randomised, double-blind, phase III study in China

W Li, G. Li, J. Li, C. Zhou et al.
ESMO Open
Cancer Immunotherapy and Biomarkers
article

107P Health-related quality of life with ivonescimab versus pembrolizumab for PD-L1 positive, non-small cell lung cancer (HARMONi-2): A randomised, double-blind, phase III study in China

W Li, G. Li, J. Li, C. Zhou, Z. Han, Y. Sun, B. Liu, J. Yao, Q. Bu, M. Zhou, Y. Zhao, H. Ge, J. Wang, S. Zhang, Y.M. Xia, Q. Shi, H. Zhong
article en

Abstract

In HARMONi-2 study, ivonescimab significantly improved progression free survival (PFS) compared with pembrolizumab in previously untreated patients with advanced PD-L1 positive non-small cell lung cancer (NSCLC), with manageable safety profile. Here we reported health-related quality of life (HRQoL) from HARMONi-2.

ESMO OpenVol. 11
Hebei Medical University (CN), Harbin Medical University (CN), Guangxi Medical University (CN), Xuzhou Medical College (CN), Kunming Medical University (CN), Shanghai Chest Hospital (CN), Chinese PLA General Hospital (CN), 307th Hospital of Chinese People’s Liberation Army (CN), Jilin Province Tumor Hospital (CN), Shandong Tumor Hospital (CN), Third Affiliated Hospital of Harbin Medical University (CN), Fourth Hospital of Hebei Medical University (CN), Jiangsu T-mab BioPharma (China) (CN), Fuzhou Dermatosis Prevention Hospital (CN), Fuzhou Pulmonary Hospital of Fujian (CN), First Affiliated Hospital of GuangXi Medical University (CN), Shanghai Pulmonary Hospital (CN), First Affiliated Hospital of Gannan Medical University (CN), First Affiliated Hospital of Henan University of Science and Technology (CN), Henan Cancer Hospital (CN), Chinese People's Liberation Army (CN), Shandong First Medical University (CN), Guangzhou Medical University (CN)
Openalex Percentile: Top 19%
Cancer Immunotherapy and Biomarkers
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