Kynurenine promotes porcine intestinal epithelial cell proliferation by activating the AHR-MST1-YAP1 axis
Together, this study has revealed a regulatory mechanism of Trp metabolism-derived Kyn in promoting porcine intestinal epithelial cell proliferation, offering insights into the connection between nutrient metabolism and intestinal epithelial homeostasis.
Authors
- Lixiao Zhang (ORCID: https://orcid.org/0000-0002-7936-9171)
- Lanmei Yin
- H. J. Yang (ORCID: https://orcid.org/0009-0004-8274-9863)
- Junhao Deng
- Xiaofeng Zhu
- Yulong Yin
- Zhenguo Hu
- Xiongzhuo Tang
- Qianqian Wang
Institutions
- Central South University (CN)
- Hunan University (CN)
- Hunan Normal University (CN)
- Institute of Subtropical Agriculture (CN)
- Third Xiangya Hospital (CN)
- Yulin University (CN)
- Hunan Agricultural University (CN)
Publication Details
- Journal
- Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
- Published
- 2026-03-17
- DOI
- https://doi.org/10.1186/s40104-026-01368-0
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00