A Decade-Long Journey of Steroid-Dependent IgA Nephropathy with Minimal Change Disease from Immunosuppressants to Rituximab and then to Obinutuzumab: A Case Report

In SD-MCD-IgAN, anti-CD20 maintenance therapy during CR reduces relapse and enables long-term steroid-free remission. If relapse occurs later, it can be controlled with low-dose steroids and resumed anti-CD20 therapy, re-establishing sustained remission.

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Publication Details

Journal
Case Reports in Nephrology and Dialysis
Published
2026-03-17
DOI
https://doi.org/10.1159/000550743
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
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article

A Decade-Long Journey of Steroid-Dependent IgA Nephropathy with Minimal Change Disease from Immunosuppressants to Rituximab and then to Obinutuzumab: A Case Report

DUQUN CHEN, Shuhua Zhu, Yuanmao Tu, Zhe Li et al.
Case Reports in Nephrology and Dialysis
Renal Diseases and Glomerulopathies
article

A Decade-Long Journey of Steroid-Dependent IgA Nephropathy with Minimal Change Disease from Immunosuppressants to Rituximab and then to Obinutuzumab: A Case Report

DUQUN CHEN, Shuhua Zhu, Yuanmao Tu, Zhe Li, Feng Xu
article en

Abstract

In SD-MCD-IgAN, anti-CD20 maintenance therapy during CR reduces relapse and enables long-term steroid-free remission. If relapse occurs later, it can be controlled with low-dose steroids and resumed anti-CD20 therapy, re-establishing sustained remission.

Case Reports in Nephrology and DialysisVol. 16(1)
Nanjing General Hospital of Nanjing Military Command (CN)
Openalex Percentile: Top 29%
Renal Diseases and Glomerulopathies
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