Racial Discrimination Accelerates Age-Related Increases in Serum Neurofilament Light Chain Among African American Women: Examination of Change from Midlife to Older Adulthood

These findings suggest that racial discrimination may contribute to the acceleration of age-related changes in sNfL, a biomarker of neurodegeneration. They further indicate that magnitude of increases in sNfL with age may be sensitive to external stressors and so highlight the potential for targeted interventions to mitigate stress-related risks for accelerated sNfL among African American women.