Tissue Eosinophil Count as a Novel Immune-Endotypic Prognostic Biomarker for Long-Term Outcomes of Posterior Nasal Neurectomy in Refractory Allergic Rhinitis
High tissue eosinophilia defines an immune-endotypic subset of RAR with attenuated response to PNN, whereas a neurogenic-dominant profile (high SP, low TEos) predicts excellent surgical prognosis. TEos count serves as a clinically actionable histopathological prognostic biomarker, facilitating personalized surgical management through immune-endotype stratification.
Authors
- Dan Su (ORCID: https://orcid.org/0000-0002-8263-0991)
- Shun Wang (ORCID: https://orcid.org/0000-0001-8832-5122)
- Yu Kong
- Song Zhang
- Yonghong Ning
Publication Details
- Journal
- International Archives of Allergy and Immunology
- Published
- 2026-03-17
- DOI
- https://doi.org/10.1159/000551497
- Primary Topic
- Allergic Rhinitis and Sensitization
- Type
- article
- Field-Weighted Citation Impact
- 0.00