A preclinical mouse model mimicking the ovarian cancer‐induced estrogen deficiency‐depression axis
The combination of intraperitoneal ovarian cancer modeling, ovariectomy, and chronic stress induction establishes a stable and clinically relevant preclinical model of hypoestrogenic ovarian cancer-related depression, suitable for translational research.
Authors
- Jianxing Liu (ORCID: https://orcid.org/0000-0002-2201-3887)
- Tingyu Zhao
- Yafei Yang
- Ping Xie
- Jing Xiao
- Danting Wen
- Chunxi Liu
Institutions
- Guangzhou University of Chinese Medicine (CN)
- State Administration of Traditional Chinese Medicine of the People's Republic of China (CN)
- Shenzhen Luohu People's Hospital (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Animal Models and Experimental Medicine
- Published
- 2026-03-16
- DOI
- https://doi.org/10.1002/ame2.70161
- Primary Topic
- Cancer, Stress, Anesthesia, and Immune Response
- Type
- article
- Field-Weighted Citation Impact
- 0.00