ATP2C2–PLA2R1 axis underlies lipid metabolism modulation and invasion in papillary thyroid carcinoma mediated by a VGIC signature
Specific VGIC gene signatures provide powerful prognostic biomarkers in PTC. Beyond improving prognosis, targeting these VGICs-especially ATP2C2-offers a novel approach to reshape the tumor metabolic microenvironment and inhibit PTC progression.
Authors
- Yinan Cao
- Wei Gao
- Linlin Sun
- Zhenxuan Sun
Institutions
- Dalian Municipal Central Hospital (CN)
- Hainan Modern Women and Children's Hospital (CN)
- Hainan Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2026-03-17
- DOI
- https://doi.org/10.1007/s12672-026-04861-0
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00