A Remarkable Tale: Increased Retinal Fluorescence Following Application of Permanent Marker Ink to Mouse Tails
These results suggest that R6G can cross the gut-blood, blood-retina, and blood-cerebrospinal fluid barriers. This raises important technical considerations for experimental mouse identification and has potential applications for fluorescence imaging and central nervous system drug targeting.
Authors
- Brent A. Bell (ORCID: https://orcid.org/0000-0003-2827-1892)
- Sierra Foshe (ORCID: https://orcid.org/0000-0001-7055-2001)
- Kimberly E. Dine (ORCID: https://orcid.org/0000-0001-5569-7261)
- Ahmara G. Ross (ORCID: https://orcid.org/0000-0002-7527-3121)
- Joseph Vithayathil (ORCID: https://orcid.org/0000-0002-1070-5237)
- Anjali Shankar
- Sarah Lee (ORCID: https://orcid.org/0000-0002-8821-6636)
- Joshua L. Dunaief
- Sophia Shi
- Ying Song
Institutions
- Children's Hospital of Philadelphia (US)
- Penn Presbyterian Medical Center (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2026-03-17
- DOI
- https://doi.org/10.1167/iovs.67.3.40
- Primary Topic
- Advanced Fluorescence Microscopy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00