Frontal Lobe and Subregional Volumetric Alterations Across Alzheimer’s Disease, Amnestic Mild Cognitive Impairment, and Vascular Dementia: An MRI Volumetry Study

Automated MRI-based volumetry revealed global frontal lobe reduction in Alzheimer's disease, whereas subregional findings were exploratory after correction for multiple testing. Frontal volumetric measures did not demonstrate a characteristic pattern in VaD. Global frontal volume may provide complementary structural information within clinically define cognitive disorders.

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Publication Details

Journal
Brain Sciences
Published
2026-03-16
DOI
https://doi.org/10.3390/brainsci16030317
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Frontal Lobe and Subregional Volumetric Alterations Across Alzheimer’s Disease, Amnestic Mild Cognitive Impairment, and Vascular Dementia: An MRI Volumetry Study

Katarina Koprivšek, Duško Kozić, Miloš Vuković, Siniša Babović et al.
Brain Sciences
Dementia and Cognitive Impairment Research
article

Frontal Lobe and Subregional Volumetric Alterations Across Alzheimer’s Disease, Amnestic Mild Cognitive Impairment, and Vascular Dementia: An MRI Volumetry Study

Katarina Koprivšek, Duško Kozić, Miloš Vuković, Siniša Babović, Stefan Stojanoski, Katarina Karher
article en

Abstract

Automated MRI-based volumetry revealed global frontal lobe reduction in Alzheimer's disease, whereas subregional findings were exploratory after correction for multiple testing. Frontal volumetric measures did not demonstrate a characteristic pattern in VaD. Global frontal volume may provide complementary structural information within clinically define cognitive disorders.

Brain SciencesVol. 16(3)
University of Novi Sad (RS)
Reduced inequalities
Openalex Percentile: Top 28%
Dementia and Cognitive Impairment Research
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