Detecting chromatin state alterations in PBMCs associated with Type 2 Diabetes Mellitus

Collectively, this study demonstrated a cost-effective and scalable solution for the routine monitoring of T2DM using PBMC chromatin biomarkers.

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Publication Details

Journal
Communications Medicine
Published
2026-03-17
DOI
https://doi.org/10.1038/s43856-026-01513-w
Primary Topic
Single-cell and spatial transcriptomics
Type
article
Field-Weighted Citation Impact
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article

Detecting chromatin state alterations in PBMCs associated with Type 2 Diabetes Mellitus

Rajshikhar Gupta, Caroline Uhler, G V Shivashankar, Maryam Moazeni Afarani et al.
Communications Medicine
Single-cell and spatial transcriptomics
article

Detecting chromatin state alterations in PBMCs associated with Type 2 Diabetes Mellitus

Rajshikhar Gupta, Caroline Uhler, G V Shivashankar, Maryam Moazeni Afarani, Issa Fetian
article en

Abstract

Collectively, this study demonstrated a cost-effective and scalable solution for the routine monitoring of T2DM using PBMC chromatin biomarkers.

Communications Medicine
Broad Institute (US), University of Basel (CH), Paul Scherrer Institute (CH), ETH Zurich (CH), Virtuelle Fabrik (Switzerland) (CH), Decision Systems (United States) (US)
Good health and well-being
Openalex Percentile: Top 19%
Single-cell and spatial transcriptomics
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