Mycetoma beyond borders: actinomycetoma in a non-endemic setting: a case report

Mycetoma is a chronic granulomatous infection mainly affecting skin and subcutaneous tissues, most commonly the foot in young adult males from tropical/subtropical rural areas.Caused by actinomycetoma or eumycetoma, it presents with progressive painless swelling, multiple sinuses, and colored-grain discharge.While endemic in the "mycetoma belt," sporadic cases occur in non-endemic regions, including Morocco, where delayed diagnosis often leads to severe deformity and amputation risk.We report a 34-year-old Moroccan man with a 2-year history of right foot swelling, fistulas, and yellowish-white grains following a splinter injury.Actinomycetoma due to Actinomadura spp. was confirmed by histopathology and culture.Extensive surgical debridement combined with prolonged triple antibiotic therapy (trimethoprim-sulfamethoxazole, amoxicillin-clavulanic acid, amikacin) achieved complete healing and no recurrence at 12 months despite osseous involvement.This case highlights the importance of considering mycetoma in chronic foot lesions in non-endemic areas and the efficacy of early combined treatment to prevent disabling sequelae.