Lower airway dysfunction in patients with chronic rhinosinusitis with nasal polyps (CRSwNP): associations with asthma, ACQ5, and inflammatory markers
Higher ACQ5 scores in CRSwNP patients, even in the absence of asthma, are independently associated with impaired lung function, small airway dysfunction, and increased AHR. These findings support the global airway concept and highlight the potential value of ACQ5 in identifying subclinical lower airway involvement in CRSwNP.
Authors
- Howraman Meteran (ORCID: https://orcid.org/0000-0001-5994-8064)
- Morten Hostrup (ORCID: https://orcid.org/0000-0002-6201-2483)
- Jens Even Tidemandsen (ORCID: https://orcid.org/0009-0006-6924-1218)
- V Backer
- Peter G Gibson
- Anne Sophie Homøe
- Kasper Aanaes
Institutions
- University of Copenhagen (DK)
- John Hunter Hospital (AU)
- Hvidovre Hospital (DK)
- Copenhagen University Hospital (DK)
- University of Newcastle Australia (AU)
Publication Details
- Journal
- Journal of Asthma
- Published
- 2026-03-17
- DOI
- https://doi.org/10.1080/02770903.2026.2645700
- Primary Topic
- Sinusitis and nasal conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00