Efficacy and safety of TPO-RA combined with sirolimus in the treatment of relapsed immune thrombocytopenia

The combination of TPO-RAs and sirolimus significantly improved platelet counts and sustained response rates. The regimen demonstrated a manageable safety profile, offering a novel therapeutic option for relapsed ITP.

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Publication Details

Journal
Hematology
Published
2026-03-17
DOI
https://doi.org/10.1080/16078454.2026.2642515
Primary Topic
Platelet Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy and safety of TPO-RA combined with sirolimus in the treatment of relapsed immune thrombocytopenia

Aoxue Tan, Yi Feng, Jinqiong Li, Jiayi Liu et al.
Hematology
Platelet Disorders and Treatments
article

Efficacy and safety of TPO-RA combined with sirolimus in the treatment of relapsed immune thrombocytopenia

Aoxue Tan, Yi Feng, Jinqiong Li, Jiayi Liu, Xi Zhang, Dan Wang, Xiaoli Chen
article en

Abstract

The combination of TPO-RAs and sirolimus significantly improved platelet counts and sustained response rates. The regimen demonstrated a manageable safety profile, offering a novel therapeutic option for relapsed ITP.

HematologyVol. 31(1)
Army Medical University (CN), Xinqiao Hospital (CN), Qujiang People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 19%
Platelet Disorders and Treatments
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