Economic Evaluation of GARDE: A Digital Health Platform for Population-Level Hereditary Cancer Risk Assessment

GARDE enables scalable hereditary cancer risk assessment within a health care provider system. Even with modest uptake, it yields a positive financial return, and significantly greater revenue is achievable with broader implementation. These findings support adoption of EHR-integrated tools to enhance clinical outcomes in precision cancer prevention and risk management, in an economically viable manner.

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Publication Details

Journal
JCO Oncology Practice
Published
2026-03-17
DOI
https://doi.org/10.1200/op-25-00708
Primary Topic
BRCA gene mutations in cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Economic Evaluation of GARDE: A Digital Health Platform for Population-Level Hereditary Cancer Risk Assessment

Chelsey R. Schlechter, Emerson Paulo Borsato, Anne C. Madeo, Richard L. Bradshaw et al.
JCO Oncology Practice
BRCA gene mutations in cancer
article

Economic Evaluation of GARDE: A Digital Health Platform for Population-Level Hereditary Cancer Risk Assessment

Chelsey R. Schlechter, Emerson Paulo Borsato, Anne C. Madeo, Richard L. Bradshaw, Caitlin G. Allen, Mary Frey, Wendy K. Kohlmann, Polina Kukhareva, Elena B. Elkin, Che Martin, Ravi N. Sharaf, Kimberly A Kaphingst, Lauren Davis-Rivera, Guilherme Del Fiol, Muhammad Danyal Ahsan, Whitney Maxwell, Kensaku Kawamoto
article en

Abstract

GARDE enables scalable hereditary cancer risk assessment within a health care provider system. Even with modest uptake, it yields a positive financial return, and significantly greater revenue is achievable with broader implementation. These findings support adoption of EHR-integrated tools to enhance clinical outcomes in precision cancer prevention and risk management, in an economically viable manner.

JCO Oncology Practice
Medical University of South Carolina (US), Cornell University (US), University of Utah (US), New York Hospital Queens (US), Huntsman Cancer Institute (US), Weill Cornell Medicine (US), Columbia University (US)
Partnerships for the goals
Openalex Percentile: Top 20%
BRCA gene mutations in cancer
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