370P Smoking cessation with cytisine in a lung cancer screening program: The RISP trial
Table: 369P 336 FHC ratio 1 st degree Mean 0.39 (0-1.44)Median 0.35 (0-0.61)FHC ratio 2 nd degree Mean 0.03 (0-0.25)Median 0 (0-0.06)FHC ratio 3 rd degree Mean 0.01 (0-0.15)Median 0 (0-0.02)Total FHC score Mean 0.43 (0-1.48)Median 0.40 (0.12-0.67) 90 th percentile threshold 0.89 (0.62-0.96) 75 th percentile threshold 0.67 (0.62-0.71)Patients included 90 th percentile 33 (9.8%)Patients included 75 th percentile 83 (24.7%) Conclusions:The observational phase of the study shows the potential utility of FHC in selecting NSCLC patients for germline mutation testing.Clinical trial identification: NCT06196424.
Authors
- Silvia Novello (ORCID: https://orcid.org/0000-0001-7653-9748)
- Salvatore Cardellicchio
- Aldo Cammarota (ORCID: https://orcid.org/0000-0003-4211-5140)
- Antonina Smedile
- Francesca Caumo (ORCID: https://orcid.org/0000-0002-9457-5176)
- Massimiliano Cani (ORCID: https://orcid.org/0000-0001-9608-4840)
- Ciro Battiloro
- Edoardo Mercadante (ORCID: https://orcid.org/0000-0003-2101-1254)
- D. Bafunno
- Ugo Pastorino
- V. Barbieri
- V. Cilenti
- B. Cosentino
- E. Davoli
- M. El Hayek
Institutions
- University of Modena and Reggio Emilia (IT)
- Centro di Riferimento Oncologico della Basilicata (IT)
- Ospedale Papa Giovanni XXIII (IT)
- Istituto Oncologico Veneto (IT)
- Azienda Ospedaliero-Universitaria Careggi (IT)
- Istituto Tumori Bari (IT)
- Azienda Ospedaliero-Universitaria "Renato Dulbecco" (IT)
- Ospedale Monaldi (IT)
- Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
- University of Turin (IT)
Publication Details
- Journal
- ESMO Open
- Published
- 2026-03-17
- DOI
- https://doi.org/10.1016/j.esmoop.2026.106683
- Primary Topic
- Smoking Behavior and Cessation
- Type
- article
- Field-Weighted Citation Impact
- 0.00