The Potential of the Inhibitors of the Transcriptional Enhanced Associate Domain Protein Factors (TEAD) as a Treatment for Cancer

The invention in this patent application relates to condensed bicyclic heteroaromatic compounds represented herein generally by formula 1. These compounds possess activities as inhibitors of TEAD, and may potentially provide therapy for treating cancer.

Authors

Publication Details

Journal
ACS Medicinal Chemistry Letters
Published
2026-03-17
DOI
https://doi.org/10.1021/acsmedchemlett.6c00134
Primary Topic
Hippo pathway signaling and YAP/TAZ
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

The Potential of the Inhibitors of the Transcriptional Enhanced Associate Domain Protein Factors (TEAD) as a Treatment for Cancer

AHMED F. ABDEL-MAGID
ACS Medicinal Chemistry Letters
Hippo pathway signaling and YAP/TAZ
article

The Potential of the Inhibitors of the Transcriptional Enhanced Associate Domain Protein Factors (TEAD) as a Treatment for Cancer

AHMED F. ABDEL-MAGID
article en

Abstract

The invention in this patent application relates to condensed bicyclic heteroaromatic compounds represented herein generally by formula 1. These compounds possess activities as inhibitors of TEAD, and may potentially provide therapy for treating cancer.

ACS Medicinal Chemistry Letters
Good health and well-being
Openalex Percentile: Top 20%
Hippo pathway signaling and YAP/TAZ
DOISourceOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.