Long‐lasting remodeling of astrocytes in an <i>Scna1</i> <sup> <i>+/−</i> </sup> mouse model of Dravet syndrome

In DS, astrocytes undergo long-term remodeling independent of tissue damage. We discuss the association between astrocyte network changes and seizures, as well as synaptic and cognitive deficits.

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Publication Details

Journal
Epilepsia
Published
2026-03-17
DOI
https://doi.org/10.1002/epi.70185
Primary Topic
Neuroscience and Neuropharmacology Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Long‐lasting remodeling of astrocytes in an Scna1 +/− mouse model of Dravet syndrome

Étienne Audinat, Alicia Janvier, Massimo Mantegazza, Noémie Cresto et al.
Epilepsia
Neuroscience and Neuropharmacology Research
article

Long‐lasting remodeling of astrocytes in an Scna1 +/− mouse model of Dravet syndrome

Étienne Audinat, Alicia Janvier, Massimo Mantegazza, Noémie Cresto, Nicola Andrea Marchi, Athénaïs Génin, Marine Blaquière, Fabrice Duprat, Romane Privé, Alexis Chaussy, Tristan Moujellil‐Legagneur
article en

Abstract

In DS, astrocytes undergo long-term remodeling independent of tissue damage. We discuss the association between astrocyte network changes and seizures, as well as synaptic and cognitive deficits.

Epilepsia
Centre National de la Recherche Scientifique (FR), Inserm (FR), Université de Montpellier (FR), Institute for Neurosciences of Montpellier (FR), Institut de Génomique Fonctionnelle (FR), Institut de Pharmacologie Moléculaire et Cellulaire (FR)
Good health and well-being
Openalex Percentile: Top 19%
Neuroscience and Neuropharmacology Research
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