Aspirin vs. Clopidogrel Monotherapy Beyond 1 Month After Percutaneous Coronary Intervention in Patients With Diabetes ― Prespecified Subgroup Analysis of the STOPDAPT-3 Trial ―

From 30 days to 1 year after PCI, cardiovascular outcomes were similar between aspirin and clopidogrel regardless of diabetes. A nominal bleeding interaction was observed; given the exploratory and underpowered subgroup analyses, this finding should be interpreted cautiously.

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Publication Details

Journal
Circulation Journal
Published
2026-03-17
DOI
https://doi.org/10.1253/circj.cj-25-1114
Primary Topic
Antiplatelet Therapy and Cardiovascular Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Aspirin vs. Clopidogrel Monotherapy Beyond 1 Month After Percutaneous Coronary Intervention in Patients With Diabetes ― Prespecified Subgroup Analysis of the STOPDAPT-3 Trial ―

Kenji Kanenawa, Mitsuru Ishii, Tsuyoshi Isawa, Hirotoshi Watanabe et al.
Circulation Journal
Antiplatelet Therapy and Cardiovascular Diseases
article

Aspirin vs. Clopidogrel Monotherapy Beyond 1 Month After Percutaneous Coronary Intervention in Patients With Diabetes ― Prespecified Subgroup Analysis of the STOPDAPT-3 Trial ―

Kenji Kanenawa, Mitsuru Ishii, Tsuyoshi Isawa, Hirotoshi Watanabe, Yohei Kobayashi, Masahiro Natsuaki, Minoru Yamada, Yoshitaka Goto, Yuki Obayashi, Tetsuzo Wakatsuki, Tomoya Kimura, Hiroyuki Takenaka, Ryoma Kawai, R Nishikawa, K Yamamoto, Tetsuya Ishikawa, Takenori Domei, Satoru Suwa, Hideki Kitahara, Takeshi Morimoto, Yoichi Nozaki, Ryuichi Kato, on behalf of the STOPDAPT-3 Investigators, Kenji Ando, Koh Ono, Takeshi Kimura
article en

Abstract

From 30 days to 1 year after PCI, cardiovascular outcomes were similar between aspirin and clopidogrel regardless of diabetes. A nominal bleeding interaction was observed; given the exploratory and underpowered subgroup analyses, this finding should be interpreted cautiously.

Circulation Journal
Hyogo Medical University (JP), Saga University (JP), Kyoto University (JP), Tenri Hospital (JP), Kyoto Medical Center (JP), Chiba University Hospital (JP), Hokko Memorial Hospital (JP), Shizuoka Saiseikai General Hospital (JP), Tokushima University Hospital (JP), Uji Hospital (JP), Juntendo University Shizuoka Hospital (JP), Osaka Red Cross Hospital (JP), Japanese Red Cross Society Wakayama Medical Center (JP), Social Insurance Saitama Chuo Hospital (JP), Kokura Memorial Hospital (JP), Municipal Hirakata City Hospital (JP), Sendai Kousei Hospital (JP), Dokkyo Medical University (JP)
Openalex Percentile: Top 28%
Antiplatelet Therapy and Cardiovascular Diseases
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