Transcriptional Activation of Estrogen Receptor-Alpha and Estrogen Receptor-Beta from Elephant Shark (Callorhynchus milii)

Overall, estrogen activation of <i>C. milii</i> ERa and ERb was similar to that for human ERa and ERb, indicating substantial conservation of the vertebrate ER during the 425 million years since the divergence of cartilaginous fish and humans from a common ancestor.

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Publication Details

Journal
Genes
Published
2026-03-17
DOI
https://doi.org/10.3390/genes17030327
Primary Topic
Reproductive biology and impacts on aquatic species
Type
article
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article

Transcriptional Activation of Estrogen Receptor-Alpha and Estrogen Receptor-Beta from Elephant Shark (Callorhynchus milii)

Haruka Narita, Ya Ao, Susumu Hyodo, Yoshinao Katsu et al.
Genes
Reproductive biology and impacts on aquatic species
article

Transcriptional Activation of Estrogen Receptor-Alpha and Estrogen Receptor-Beta from Elephant Shark (Callorhynchus milii)

Haruka Narita, Ya Ao, Susumu Hyodo, Yoshinao Katsu, Michael E. Baker, Wataru Takagi
article en

Abstract

Overall, estrogen activation of <i>C. milii</i> ERa and ERb was similar to that for human ERa and ERb, indicating substantial conservation of the vertebrate ER during the 425 million years since the divergence of cartilaginous fish and humans from a common ancestor.

GenesVol. 17(3)
Hokkaido University (JP), University of California San Diego (US), The University of Tokyo (JP)
Life below water
Openalex Percentile: Top 17%
Reproductive biology and impacts on aquatic species
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