Amantadine Enhances IL‐10 Expressions to Maintain the Renal Functions Against Inflammation and Oxidative Stress via Increasing PI3K/AKT/HIF‐1α Pathway and Decreasing AQP2–4 Signallings
In this study, AMA treatment exhibited anti-inflammatory effects on kidney tissue via several different mechanisms. However, additional studies with varied doses and durations of AMA treatment, involving different pathways and detailed analyses, are necessary.
Authors
- Esma Selçuk (ORCID: https://orcid.org/0000-0002-1481-7834)
- Orhan Berk İmeci (ORCID: https://orcid.org/0000-0002-3850-0137)
- İlter İLHAN İLHAN
- Öznur Kolay (ORCID: https://orcid.org/0009-0002-3768-7996)
- Muhammet Yusuf TEPEBAŞI
- Pinar Aslan Kosar
- Alim Kosar
- Ozlem Ozmen
- Halil Asci
Institutions
- Süleyman Demirel Üniversitesi (TR)
- Suleyman Demirel University (KZ)
- Burdur Mehmet Akif Ersoy Üniversitesi (TR)
Publication Details
- Journal
- Basic & Clinical Pharmacology & Toxicology
- Published
- 2026-03-17
- DOI
- https://doi.org/10.1111/bcpt.70216
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00