Deregulated miR-487b-3p in Patients with Non-Alcoholic Fatty Liver Disease and Its Regulatory Effect on Insulin Resistance

miR-487b-3p may serve as a potential diagnostic biomarker for NAFLD, and miR-487b-3p negatively regulates IRS1 to modulate glucose uptake, thereby impairing insulin sensitivity in NAFLD patients.

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Publication Details

Journal
The Turkish Journal of Gastroenterology
Published
2026-03-16
DOI
https://doi.org/10.5152/tjg.2026.25649
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Deregulated miR-487b-3p in Patients with Non-Alcoholic Fatty Liver Disease and Its Regulatory Effect on Insulin Resistance

Yuanyuan Lu, Ting Zhan, Mingtao Chen, Min Huang et al.
The Turkish Journal of Gastroenterology
Liver Disease Diagnosis and Treatment
article

Deregulated miR-487b-3p in Patients with Non-Alcoholic Fatty Liver Disease and Its Regulatory Effect on Insulin Resistance

Yuanyuan Lu, Ting Zhan, Mingtao Chen, Min Huang, Meng Liu, Xia Tian, Jie Tan, Zheng Han
article en

Abstract

miR-487b-3p may serve as a potential diagnostic biomarker for NAFLD, and miR-487b-3p negatively regulates IRS1 to modulate glucose uptake, thereby impairing insulin sensitivity in NAFLD patients.

The Turkish Journal of Gastroenterology
Wuhan Third Hospital (CN)
Good health and well-being
Openalex Percentile: Top 21%
Liver Disease Diagnosis and Treatment
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