Longitudinal analysis of peripheral blood immune status and prognosis dynamic prediction for advanced colon cancer with first-line chemotherapy

This study highlights the prognostic significance of measuring longitudinal immune status in advanced CRC patients and develops an internally validated dynamic prediction model. External validation is needed before clinical implementation.

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Publication Details

Journal
Cancer Immunology Immunotherapy
Published
2026-03-17
DOI
https://doi.org/10.1007/s00262-025-04295-7
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
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article

Longitudinal analysis of peripheral blood immune status and prognosis dynamic prediction for advanced colon cancer with first-line chemotherapy

D. Liu, Fan Wang, Qingguo Wang, Xun Cai et al.
Cancer Immunology Immunotherapy
Cancer Immunotherapy and Biomarkers
article

Longitudinal analysis of peripheral blood immune status and prognosis dynamic prediction for advanced colon cancer with first-line chemotherapy

D. Liu, Fan Wang, Qingguo Wang, Xun Cai, Q. Y. Li, Chun-xia Li, Jin-Yan Zhao, Tao Zhang
article en

Abstract

This study highlights the prognostic significance of measuring longitudinal immune status in advanced CRC patients and develops an internally validated dynamic prediction model. External validation is needed before clinical implementation.

Cancer Immunology ImmunotherapyVol. 75(4)
Shandong University (CN), Shanghai Jiao Tong University (CN), Shanghai Cancer Institute (CN), Shanghai First People's Hospital (CN), Tianjin Medical University (CN)
Reduced inequalities
Openalex Percentile: Top 19%
Cancer Immunotherapy and Biomarkers
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