Osteoporosis in chronic kidney disease: diagnostic dilemmas and therapeutic controversies

In the absence of evidence-based treatment protocols for CKD-associated osteoporosis, fracture prevention should rely on pragmatic individualized risk assessment. Optimization of mineral metabolism and cautious use of bone-targeting therapies in high-risk patients are key components of management strategy. Future studies should prioritize CKD-specific fracture outcomes and validated diagnostic strategies to guide treatment decisions.

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Publication Details

Journal
Expert Review of Endocrinology & Metabolism
Published
2026-03-17
DOI
https://doi.org/10.1080/17446651.2026.2646161
Primary Topic
Parathyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Osteoporosis in chronic kidney disease: diagnostic dilemmas and therapeutic controversies

Marie Houmaa Vrist, Hanne Skou Jørgensen, Bente Langdahl, S. Sakthivel
Expert Review of Endocrinology & Metabolism
Parathyroid Disorders and Treatments
article

Osteoporosis in chronic kidney disease: diagnostic dilemmas and therapeutic controversies

Marie Houmaa Vrist, Hanne Skou Jørgensen, Bente Langdahl, S. Sakthivel
article en

Abstract

In the absence of evidence-based treatment protocols for CKD-associated osteoporosis, fracture prevention should rely on pragmatic individualized risk assessment. Optimization of mineral metabolism and cautious use of bone-targeting therapies in high-risk patients are key components of management strategy. Future studies should prioritize CKD-specific fracture outcomes and validated diagnostic strategies to guide treatment decisions.

Expert Review of Endocrinology & Metabolism
Aarhus University (DK), Aarhus University Hospital (DK), University Clinic for Nephrology and Hypertension, Diabetology and Endocrinology (DE)
Good health and well-being
Openalex Percentile: Top 29%
Parathyroid Disorders and Treatments
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